| Fixtures |
| Date | Time | Home Team | Score | Away Team |
| Results |
| Date | Time | Home Team | Score | Away Team |
| 03/02/2013 | 23:30 | San Francisco | 31 - 34 | Baltimore |
| 28/01/2013 | 00:00 | NFC | 62 - 35 | AFC |
| 20/01/2013 | 23:30 | New England | 13 - 28 | Baltimore |
| 20/01/2013 | 20:00 | Atlanta | 24 - 28 | San Francisco |
| 13/01/2013 | 21:30 | New England | 41 - 28 | Houston |
| 13/01/2013 | 18:00 | Atlanta | 30 - 28 | Seattle |
| 13/01/2013 | 01:00 | San Francisco | 45 - 31 | Green Bay |
| 12/01/2013 | 21:30 | Denver | 35 - 38 | Baltimore |
| 06/01/2013 | 21:30 | Washington | 14 - 24 | Seattle |
| 06/01/2013 | 18:00 | Baltimore | 24 - 9 | Indianapolis |
| 06/01/2013 | 01:00 | Green Bay | 24 - 10 | Minnesota |
| 05/01/2013 | 21:30 | Houston | 19 - 13 | Cincinnati |
| 31/12/2012 | 01:20 | Washington | 28 - 18 | Dallas |
| 30/12/2012 | 21:25 | Minnesota | 37 - 34 | Green Bay |
| 30/12/2012 | 21:25 | Seattle | 20 - 13 | St. Louis |
| 30/12/2012 | 21:25 | New England | 28 - 0 | Miami |
| 30/12/2012 | 21:25 | Denver | 38 - 3 | Kansas City |
| 30/12/2012 | 21:25 | San Diego | 24 - 21 | Oakland |
| 30/12/2012 | 21:25 | San Francisco | 27 - 13 | Arizona |
| 30/12/2012 | 18:00 | Buffalo | 28 - 9 | N.Y. Jets |
| 30/12/2012 | 18:00 | New Orleans | 38 - 44 | Carolina |
| 30/12/2012 | 18:00 | Cincinnati | 23 - 17 | Baltimore |
| 30/12/2012 | 18:00 | Pittsburgh | 24 - 10 | Cleveland |
| 30/12/2012 | 18:00 | Indianapolis | 28 - 16 | Houston |
| 30/12/2012 | 18:00 | Tennessee | 38 - 20 | Jacksonville |
| 30/12/2012 | 18:00 | N.Y. Giants | 42 - 7 | Philadelphia |
| 30/12/2012 | 18:00 | Atlanta | 17 - 22 | Tampa Bay |
| 30/12/2012 | 18:00 | Detroit | 24 - 26 | Chicago |
| 24/12/2012 | 01:20 | Seattle | 42 - 13 | San Francisco |
| 23/12/2012 | 21:25 | Arizona | 13 - 28 | Chicago |
| 23/12/2012 | 21:25 | Baltimore | 33 - 14 | N.Y. Giants |
| 23/12/2012 | 21:05 | Denver | 34 - 12 | Cleveland |
| 23/12/2012 | 18:00 | Carolina | 17 - 6 | Oakland |
| 23/12/2012 | 18:00 | Pittsburgh | 10 - 13 | Cincinnati |
| 23/12/2012 | 18:00 | Jacksonville | 16 - 23 | New England |
| 23/12/2012 | 18:00 | Kansas City | 13 - 20 | Indianapolis |
| 23/12/2012 | 18:00 | Dallas | 31 - 34 | New Orleans |
| 23/12/2012 | 18:00 | Philadelphia | 20 - 27 | Washington |
| 23/12/2012 | 18:00 | Tampa Bay | 13 - 28 | St. Louis |
| 23/12/2012 | 18:00 | Houston | 6 - 23 | Minnesota |
| 23/12/2012 | 18:00 | N.Y. Jets | 17 - 27 | San Diego |
| 23/12/2012 | 18:00 | Miami | 24 - 10 | Buffalo |
| 23/12/2012 | 18:00 | Green Bay | 55 - 7 | Tennessee |
| 23/12/2012 | 01:30 | Detroit | 18 - 31 | Atlanta |
| 18/12/2012 | 01:30 | Tennessee | 14 - 10 | N.Y. Jets |
| 17/12/2012 | 01:20 | New England | 34 - 41 | San Francisco |
| 16/12/2012 | 21:25 | Oakland | 15 - 0 | Kansas City |
| 16/12/2012 | 21:25 | Dallas | 27 - 24 | Pittsburgh |
| 16/12/2012 | 21:05 | Arizona | 38 - 10 | Detroit |
| 16/12/2012 | 21:05 | San Diego | 7 - 31 | Carolina |
| 16/12/2012 | 21:05 | Buffalo | 17 - 50 | Seattle |
| 16/12/2012 | 18:00 | Chicago | 13 - 21 | Green Bay |
| 16/12/2012 | 18:00 | Atlanta | 34 - 0 | N.Y. Giants |
| 16/12/2012 | 18:00 | New Orleans | 41 - 0 | Tampa Bay |
| 16/12/2012 | 18:00 | St. Louis | 22 - 36 | Minnesota |
| 16/12/2012 | 18:00 | Cleveland | 21 - 38 | Washington |
| 16/12/2012 | 18:00 | Miami | 24 - 3 | Jacksonville |
| 16/12/2012 | 18:00 | Baltimore | 17 - 34 | Denver |
| 16/12/2012 | 18:00 | Houston | 29 - 17 | Indianapolis |
| 14/12/2012 | 01:20 | Philadelphia | 13 - 34 | Cincinnati |
| 11/12/2012 | 01:30 | New England | 42 - 14 | Houston |
| 10/12/2012 | 01:20 | Green Bay | 27 - 20 | Detroit |
| 09/12/2012 | 21:25 | N.Y. Giants | 52 - 27 | New Orleans |
| 09/12/2012 | 21:25 | Seattle | 58 - 0 | Arizona |
| 09/12/2012 | 21:05 | San Francisco | 27 - 13 | Miami |
| 09/12/2012 | 18:00 | Washington | 31 - 28 | Baltimore |
| 09/12/2012 | 18:00 | Cleveland | 30 - 7 | Kansas City |
| 09/12/2012 | 18:00 | Pittsburgh | 24 - 34 | San Diego |
| 09/12/2012 | 18:00 | Indianapolis | 27 - 23 | Tennessee |
| 09/12/2012 | 18:00 | Jacksonville | 10 - 17 | N.Y. Jets |
| 09/12/2012 | 18:00 | Minnesota | 21 - 14 | Chicago |
| 09/12/2012 | 18:00 | Carolina | 30 - 20 | Atlanta |
| 09/12/2012 | 18:00 | Tampa Bay | 21 - 23 | Philadelphia |
| 09/12/2012 | 18:00 | Buffalo | 12 - 15 | St. Louis |
| 09/12/2012 | 18:00 | Cincinnati | 19 - 20 | Dallas |
| 07/12/2012 | 01:20 | Oakland | 13 - 26 | Denver |
| 04/12/2012 | 01:30 | Washington | 17 - 16 | N.Y. Giants |
| 03/12/2012 | 01:20 | Dallas | 38 - 33 | Philadelphia |
| 02/12/2012 | 21:25 | Baltimore | 20 - 23 | Pittsburgh |
| 02/12/2012 | 21:25 | Oakland | 17 - 20 | Cleveland |
| 02/12/2012 | 21:25 | San Diego | 13 - 20 | Cincinnati |
| 02/12/2012 | 21:05 | Denver | 31 - 23 | Tampa Bay |
| 02/12/2012 | 18:00 | Chicago | 17 - 23 | Seattle |
| 02/12/2012 | 18:00 | Green Bay | 23 - 14 | Minnesota |
| 02/12/2012 | 18:00 | St. Louis | 16 - 13 | San Francisco |
| 02/12/2012 | 18:00 | N.Y. Jets | 7 - 6 | Arizona |
| 02/12/2012 | 18:00 | Kansas City | 27 - 21 | Carolina |
| 02/12/2012 | 18:00 | Detroit | 33 - 35 | Indianapolis |
| 02/12/2012 | 18:00 | Buffalo | 34 - 18 | Jacksonville |
| 02/12/2012 | 18:00 | Miami | 16 - 23 | New England |
| 02/12/2012 | 18:00 | Tennessee | 10 - 24 | Houston |
| 30/11/2012 | 01:20 | Atlanta | 23 - 13 | New Orleans |
| 27/11/2012 | 01:30 | Philadelphia | 22 - 30 | Carolina |
| 26/11/2012 | 01:20 | N.Y. Giants | 38 - 10 | Green Bay |
| 25/11/2012 | 21:25 | Arizona | 17 - 31 | St. Louis |
| 25/11/2012 | 21:25 | New Orleans | 21 - 31 | San Francisco |
| 25/11/2012 | 21:05 | San Diego | 13 - 16 | Baltimore |
| 25/11/2012 | 18:00 | Miami | 24 - 21 | Seattle |
| 25/11/2012 | 18:00 | Tampa Bay | 23 - 24 | Atlanta |
| 25/11/2012 | 18:00 | Chicago | 28 - 10 | Minnesota |
| 25/11/2012 | 18:00 | Kansas City | 9 - 17 | Denver |
| 25/11/2012 | 18:00 | Jacksonville | 24 - 19 | Tennessee |
| 25/11/2012 | 18:00 | Indianapolis | 20 - 13 | Buffalo |
| 25/11/2012 | 18:00 | Cleveland | 20 - 14 | Pittsburgh |
| 25/11/2012 | 18:00 | Cincinnati | 34 - 10 | Oakland |
| 23/11/2012 | 01:20 | N.Y. Jets | 19 - 49 | New England |
| 22/11/2012 | 21:15 | Dallas | 31 - 38 | Washington |
| 22/11/2012 | 17:30 | Detroit | 31 - 34 | Houston |
| 20/11/2012 | 01:30 | San Francisco | 32 - 7 | Chicago |
| 19/11/2012 | 01:20 | Pittsburgh | 10 - 13 | Baltimore |
| 18/11/2012 | 21:25 | New England | 59 - 24 | Indianapolis |
| 18/11/2012 | 21:25 | Denver | 30 - 23 | San Diego |
| 18/11/2012 | 21:05 | Oakland | 17 - 38 | New Orleans |
| 18/11/2012 | 18:00 | Washington | 31 - 6 | Philadelphia |
| 18/11/2012 | 18:00 | Detroit | 20 - 24 | Green Bay |
| 18/11/2012 | 18:00 | Atlanta | 23 - 19 | Arizona |
| 18/11/2012 | 18:00 | Carolina | 21 - 27 | Tampa Bay |
| 18/11/2012 | 18:00 | Dallas | 23 - 20 | Cleveland |
| 18/11/2012 | 18:00 | St. Louis | 13 - 27 | N.Y. Jets |
| 18/11/2012 | 18:00 | Houston | 43 - 37 | Jacksonville |
| 18/11/2012 | 18:00 | Kansas City | 6 - 28 | Cincinnati |
| 16/11/2012 | 01:20 | Buffalo | 19 - 14 | Miami |
| 13/11/2012 | 01:30 | Pittsburgh | 16 - 13 | Kansas City |
| 12/11/2012 | 01:20 | Chicago | 6 - 13 | Houston |
| 11/11/2012 | 21:25 | San Francisco | 24 - 24 | St. Louis |
| 11/11/2012 | 21:25 | Philadelphia | 23 - 38 | Dallas |
| 11/11/2012 | 21:05 | Seattle | 28 - 7 | N.Y. Jets |
| 11/11/2012 | 18:00 | Minnesota | 34 - 24 | Detroit |
| 11/11/2012 | 18:00 | New Orleans | 31 - 27 | Atlanta |
| 11/11/2012 | 18:00 | Cincinnati | 31 - 13 | N.Y. Giants |
| 11/11/2012 | 18:00 | Baltimore | 55 - 20 | Oakland |
| 11/11/2012 | 18:00 | New England | 37 - 31 | Buffalo |
| 11/11/2012 | 18:00 | Miami | 3 - 37 | Tennessee |
| 11/11/2012 | 18:00 | Tampa Bay | 34 - 24 | San Diego |
| 11/11/2012 | 18:00 | Carolina | 14 - 36 | Denver |
| 09/11/2012 | 01:20 | Jacksonville | 10 - 27 | Indianapolis |
| 06/11/2012 | 01:30 | New Orleans | 28 - 13 | Philadelphia |
| 05/11/2012 | 01:20 | Atlanta | 19 - 13 | Dallas |
| 04/11/2012 | 21:25 | N.Y. Giants | 20 - 24 | Pittsburgh |
| 04/11/2012 | 21:05 | Oakland | 32 - 42 | Tampa Bay |
| 04/11/2012 | 21:05 | Seattle | 30 - 20 | Minnesota |
| 04/11/2012 | 18:00 | Washington | 13 - 21 | Carolina |
| 04/11/2012 | 18:00 | Green Bay | 31 - 17 | Arizona |
| 04/11/2012 | 18:00 | Jacksonville | 14 - 31 | Detroit |
| 04/11/2012 | 18:00 | Tennessee | 20 - 51 | Chicago |
| 04/11/2012 | 18:00 | Cincinnati | 23 - 31 | Denver |
| 04/11/2012 | 18:00 | Cleveland | 15 - 25 | Baltimore |
| 04/11/2012 | 18:00 | Houston | 21 - 9 | Buffalo |
| 04/11/2012 | 18:00 | Indianapolis | 23 - 20 | Miami |
| 02/11/2012 | 00:20 | San Diego | 31 - 13 | Kansas City |
| 30/10/2012 | 00:30 | Arizona | 3 - 24 | San Francisco |
| 29/10/2012 | 00:20 | Denver | 34 - 14 | New Orleans |
| 28/10/2012 | 20:25 | Dallas | 24 - 29 | N.Y. Giants |
| 28/10/2012 | 20:05 | Kansas City | 16 - 26 | Oakland |
| 28/10/2012 | 17:00 | Green Bay | 24 - 15 | Jacksonville |
| 28/10/2012 | 17:00 | N.Y. Jets | 9 - 30 | Miami |
| 28/10/2012 | 17:00 | Cleveland | 7 - 6 | San Diego |
| 28/10/2012 | 17:00 | Tennessee | 13 - 19 | Indianapolis |
| 28/10/2012 | 17:00 | St. Louis | 7 - 45 | New England |
| 28/10/2012 | 17:00 | Philadelphia | 17 - 30 | Atlanta |
| 28/10/2012 | 17:00 | Chicago | 23 - 22 | Carolina |
| 28/10/2012 | 17:00 | Detroit | 28 - 24 | Seattle |
| 28/10/2012 | 17:00 | Pittsburgh | 27 - 12 | Washington |
| 26/10/2012 | 01:20 | Minnesota | 17 - 36 | Tampa Bay |
| 23/10/2012 | 01:30 | Chicago | 13 - 7 | Detroit |
| 22/10/2012 | 01:20 | Cincinnati | 17 - 24 | Pittsburgh |
| 21/10/2012 | 21:25 | Oakland | 26 - 23 | Jacksonville |
| 21/10/2012 | 21:25 | New England | 29 - 26 | N.Y. Jets |
| 21/10/2012 | 18:00 | N.Y. Giants | 27 - 23 | Washington |
| 21/10/2012 | 18:00 | Minnesota | 21 - 14 | Arizona |
| 21/10/2012 | 18:00 | Carolina | 14 - 19 | Dallas |
| 21/10/2012 | 18:00 | Tampa Bay | 28 - 35 | New Orleans |
| 21/10/2012 | 18:00 | St. Louis | 20 - 30 | Green Bay |
| 21/10/2012 | 18:00 | Houston | 43 - 13 | Baltimore |
| 21/10/2012 | 18:00 | Indianapolis | 17 - 13 | Cleveland |
| 21/10/2012 | 18:00 | Buffalo | 34 - 35 | Tennessee |
| 19/10/2012 | 01:20 | San Francisco | 13 - 6 | Seattle |
| 16/10/2012 | 01:30 | San Diego | 24 - 35 | Denver |
| 15/10/2012 | 01:20 | Houston | 24 - 42 | Green Bay |
| 14/10/2012 | 21:25 | San Francisco | 3 - 26 | N.Y. Giants |
| 14/10/2012 | 21:25 | Washington | 38 - 26 | Minnesota |
| 14/10/2012 | 21:05 | Seattle | 24 - 23 | New England |
| 14/10/2012 | 21:05 | Arizona | 16 - 19 | Buffalo |
| 14/10/2012 | 18:00 | Atlanta | 23 - 20 | Oakland |
| 14/10/2012 | 18:00 | Tampa Bay | 38 - 10 | Kansas City |
| 14/10/2012 | 18:00 | N.Y. Jets | 35 - 9 | Indianapolis |
| 14/10/2012 | 18:00 | Cleveland | 34 - 24 | Cincinnati |
| 14/10/2012 | 18:00 | Philadelphia | 23 - 26 | Detroit |
| 14/10/2012 | 18:00 | Miami | 17 - 14 | St. Louis |
| 14/10/2012 | 18:00 | Baltimore | 31 - 29 | Dallas |
| 12/10/2012 | 01:20 | Tennessee | 26 - 23 | Pittsburgh |
| 09/10/2012 | 01:30 | N.Y. Jets | 17 - 23 | Houston |
| 08/10/2012 | 01:20 | New Orleans | 31 - 24 | San Diego |
| 07/10/2012 | 21:25 | Minnesota | 30 - 7 | Tennessee |
| 07/10/2012 | 21:25 | San Francisco | 45 - 3 | Buffalo |
| 07/10/2012 | 21:25 | New England | 31 - 21 | Denver |
| 07/10/2012 | 21:05 | Jacksonville | 3 - 41 | Chicago |
| 07/10/2012 | 21:05 | Carolina | 12 - 16 | Seattle |
| 07/10/2012 | 18:00 | Washington | 17 - 24 | Atlanta |
| 07/10/2012 | 18:00 | Pittsburgh | 16 - 14 | Philadelphia |
| 07/10/2012 | 18:00 | Indianapolis | 30 - 27 | Green Bay |
| 07/10/2012 | 18:00 | N.Y. Giants | 41 - 27 | Cleveland |
| 07/10/2012 | 18:00 | Cincinnati | 13 - 17 | Miami |
| 07/10/2012 | 18:00 | Kansas City | 6 - 9 | Baltimore |
| 05/10/2012 | 01:20 | St. Louis | 17 - 3 | Arizona |
| 02/10/2012 | 01:30 | Dallas | 18 - 34 | Chicago |
| 01/10/2012 | 01:20 | Philadelphia | 19 - 17 | N.Y. Giants |
| 30/09/2012 | 21:25 | Green Bay | 28 - 27 | New Orleans |
| 30/09/2012 | 21:25 | Tampa Bay | 22 - 24 | Washington |
| 30/09/2012 | 21:05 | Jacksonville | 10 - 27 | Cincinnati |
| 30/09/2012 | 21:05 | Denver | 37 - 6 | Oakland |
| 30/09/2012 | 21:05 | Arizona | 24 - 21 | Miami |
| 30/09/2012 | 18:00 | Buffalo | 28 - 52 | New England |
| 30/09/2012 | 18:00 | Houston | 38 - 14 | Tennessee |
| 30/09/2012 | 18:00 | Kansas City | 20 - 37 | San Diego |
| 30/09/2012 | 18:00 | Detroit | 13 - 20 | Minnesota |
| 30/09/2012 | 18:00 | Atlanta | 30 - 28 | Carolina |
| 30/09/2012 | 18:00 | St. Louis | 19 - 13 | Seattle |
| 30/09/2012 | 18:00 | N.Y. Jets | 0 - 34 | San Francisco |
| 28/09/2012 | 01:20 | Baltimore | 23 - 16 | Cleveland |
| 25/09/2012 | 01:30 | Seattle | 14 - 12 | Green Bay |
| 24/09/2012 | 01:20 | Baltimore | 31 - 30 | New England |
| 23/09/2012 | 21:25 | Denver | 25 - 31 | Houston |
| 23/09/2012 | 21:25 | Oakland | 34 - 31 | Pittsburgh |
| 23/09/2012 | 21:05 | San Diego | 3 - 27 | Atlanta |
| 23/09/2012 | 21:05 | Arizona | 27 - 6 | Philadelphia |
| 23/09/2012 | 18:00 | Dallas | 16 - 10 | Tampa Bay |
| 23/09/2012 | 18:00 | Chicago | 23 - 6 | St. Louis |
| 23/09/2012 | 18:00 | Minnesota | 24 - 13 | San Francisco |
| 23/09/2012 | 18:00 | Tennessee | 44 - 41 | Detroit |
| 23/09/2012 | 18:00 | Washington | 31 - 38 | Cincinnati |
| 23/09/2012 | 18:00 | New Orleans | 24 - 27 | Kansas City |
| 23/09/2012 | 18:00 | Miami | 20 - 23 | N.Y. Jets |
| 23/09/2012 | 18:00 | Cleveland | 14 - 24 | Buffalo |
| 23/09/2012 | 18:00 | Indianapolis | 17 - 22 | Jacksonville |
| 21/09/2012 | 01:20 | Carolina | 7 - 36 | N.Y. Giants |
| 18/09/2012 | 01:30 | Atlanta | 27 - 21 | Denver |
| 17/09/2012 | 01:20 | San Francisco | 27 - 19 | Detroit |
| 16/09/2012 | 21:25 | Pittsburgh | 27 - 10 | N.Y. Jets |
| 16/09/2012 | 21:25 | San Diego | 38 - 10 | Tennessee |
| 16/09/2012 | 21:05 | St. Louis | 31 - 28 | Washington |
| 16/09/2012 | 21:05 | Seattle | 27 - 7 | Dallas |
| 16/09/2012 | 18:00 | N.Y. Giants | 41 - 34 | Tampa Bay |
| 16/09/2012 | 18:00 | Carolina | 35 - 27 | New Orleans |
| 16/09/2012 | 18:00 | New England | 18 - 20 | Arizona |
| 16/09/2012 | 18:00 | Indianapolis | 23 - 20 | Minnesota |
| 16/09/2012 | 18:00 | Philadelphia | 24 - 23 | Baltimore |
| 16/09/2012 | 18:00 | Buffalo | 35 - 17 | Kansas City |
| 16/09/2012 | 18:00 | Cincinnati | 34 - 27 | Cleveland |
| 16/09/2012 | 18:00 | Jacksonville | 7 - 27 | Houston |
| 16/09/2012 | 18:00 | Miami | 35 - 13 | Oakland |
| 14/09/2012 | 01:20 | Green Bay | 23 - 10 | Chicago |
| 11/09/2012 | 03:15 | Oakland | 14 - 22 | San Diego |
| 11/09/2012 | 00:00 | Baltimore | 44 - 13 | Cincinnati |
| 10/09/2012 | 01:20 | Denver | 31 - 19 | Pittsburgh |
| 09/09/2012 | 21:25 | Tampa Bay | 16 - 10 | Carolina |
| 09/09/2012 | 21:25 | Arizona | 20 - 16 | Seattle |
| 09/09/2012 | 21:25 | Green Bay | 22 - 30 | San Francisco |
| 09/09/2012 | 18:00 | Chicago | 41 - 21 | Indianapolis |
| 09/09/2012 | 18:00 | Minnesota | 26 - 23 | Jacksonville |
| 09/09/2012 | 18:00 | N.Y. Jets | 48 - 28 | Buffalo |
| 09/09/2012 | 18:00 | Houston | 30 - 10 | Miami |
| 09/09/2012 | 18:00 | Tennessee | 13 - 34 | New England |
| 09/09/2012 | 18:00 | Detroit | 27 - 23 | St. Louis |
| 09/09/2012 | 18:00 | New Orleans | 32 - 40 | Washington |
| 09/09/2012 | 18:00 | Cleveland | 16 - 17 | Philadelphia |
| 09/09/2012 | 18:00 | Kansas City | 24 - 40 | Atlanta |
| 06/09/2012 | 01:30 | N.Y. Giants | 17 - 24 | Dallas |
| 31/08/2012 | 04:00 | Arizona | 13 - 16 | Denver |
| 31/08/2012 | 03:00 | San Francisco | 35 - 3 | San Diego |
| 31/08/2012 | 03:00 | Seattle | 21 - 3 | Oakland |
| 31/08/2012 | 00:30 | Cleveland | 20 - 28 | Chicago |
| 31/08/2012 | 00:00 | Houston | 28 - 24 | Minnesota |
| 31/08/2012 | 00:00 | Detroit | 38 - 32 | Buffalo |
| 31/08/2012 | 00:00 | Green Bay | 24 - 3 | Kansas City |
| 31/08/2012 | 00:00 | Tennessee | 10 - 6 | New Orleans |
| 31/08/2012 | 00:00 | Indianapolis | 20 - 16 | Cincinnati |
| 31/08/2012 | 00:00 | Pittsburgh | 17 - 16 | Carolina |
| 31/08/2012 | 00:00 | St. Louis | 31 - 17 | Baltimore |
| 30/08/2012 | 23:35 | Philadelphia | 28 - 10 | N.Y. Jets |
| 30/08/2012 | 23:30 | Jacksonville | 24 - 14 | Atlanta |
| 30/08/2012 | 01:30 | Dallas | 30 - 13 | Miami |
| 30/08/2012 | 00:00 | Washington | 30 - 3 | Tampa Bay |
| 30/08/2012 | 00:00 | N.Y. Giants | 6 - 3 | New England |
| 27/08/2012 | 01:00 | N.Y. Jets | 12 - 17 | Carolina |
| 26/08/2012 | 21:00 | Denver | 24 - 29 | San Francisco |
| 26/08/2012 | 01:00 | Dallas | 20 - 19 | St. Louis |
| 26/08/2012 | 01:00 | New Orleans | 34 - 27 | Houston |
| 26/08/2012 | 00:00 | Oakland | 31 - 20 | Detroit |
| 26/08/2012 | 00:00 | Buffalo | 7 - 38 | Pittsburgh |
| 25/08/2012 | 21:00 | Washington | 30 - 17 | Indianapolis |
| 25/08/2012 | 01:00 | Minnesota | 10 - 12 | San Diego |
| 25/08/2012 | 01:00 | N.Y. Giants | 17 - 20 | Chicago |
| 25/08/2012 | 01:00 | Kansas City | 14 - 44 | Seattle |
| 25/08/2012 | 00:30 | Tampa Bay | 30 - 28 | New England |
| 25/08/2012 | 00:30 | Miami | 6 - 23 | Atlanta |
| 25/08/2012 | 00:30 | Cleveland | 10 - 27 | Philadelphia |
| 24/08/2012 | 01:00 | Tennessee | 32 - 27 | Arizona |
| 24/08/2012 | 00:30 | Baltimore | 48 - 17 | Jacksonville |
| 24/08/2012 | 00:00 | Cincinnati | 13 - 27 | Green Bay |
| 21/08/2012 | 01:00 | New England | 17 - 27 | Philadelphia |
| 20/08/2012 | 01:00 | Pittsburgh | 26 - 24 | Indianapolis |
| 19/08/2012 | 02:00 | San Diego | 28 - 20 | Dallas |
| 19/08/2012 | 02:00 | Denver | 10 - 30 | Seattle |
| 19/08/2012 | 01:00 | Houston | 20 - 9 | San Francisco |
| 19/08/2012 | 01:00 | Chicago | 33 - 31 | Washington |
| 19/08/2012 | 01:00 | St. Louis | 31 - 17 | Kansas City |
| 19/08/2012 | 00:00 | N.Y. Jets | 3 - 26 | N.Y. Giants |
| 18/08/2012 | 03:00 | Arizona | 31 - 27 | Oakland |
| 18/08/2012 | 01:00 | Carolina | 23 - 17 | Miami |
| 18/08/2012 | 01:00 | Baltimore | 12 - 27 | Detroit |
| 18/08/2012 | 01:00 | Minnesota | 36 - 14 | Buffalo |
| 18/08/2012 | 01:00 | New Orleans | 24 - 27 | Jacksonville |
| 18/08/2012 | 00:30 | Tampa Bay | 7 - 30 | Tennessee |
| 17/08/2012 | 01:00 | Green Bay | 10 - 35 | Cleveland |
| 17/08/2012 | 01:00 | Atlanta | 19 - 24 | Cincinnati |
| 14/08/2012 | 01:00 | Oakland | 0 - 3 | Dallas |
| 12/08/2012 | 18:30 | Indianapolis | 38 - 3 | St. Louis |
| 12/08/2012 | 03:00 | Seattle | 27 - 17 | Tennessee |
| 12/08/2012 | 00:00 | Carolina | 13 - 26 | Houston |
| 11/08/2012 | 02:00 | San Francisco | 17 - 6 | Minnesota |
| 11/08/2012 | 01:00 | Kansas City | 27 - 17 | Arizona |
| 11/08/2012 | 00:30 | Miami | 7 - 20 | Tampa Bay |
| 11/08/2012 | 00:30 | Cincinnati | 17 - 6 | N.Y. Jets |
| 11/08/2012 | 00:30 | Detroit | 17 - 19 | Cleveland |
| 11/08/2012 | 00:30 | Jacksonville | 32 - 31 | N.Y. Giants |
| 10/08/2012 | 01:30 | Chicago | 3 - 31 | Denver |
| 10/08/2012 | 01:00 | San Diego | 21 - 13 | Green Bay |
| 10/08/2012 | 00:30 | Atlanta | 17 - 31 | Baltimore |
| 10/08/2012 | 00:30 | Philadelphia | 24 - 23 | Pittsburgh |
| 10/08/2012 | 00:30 | New England | 7 - 6 | New Orleans |
| 10/08/2012 | 00:00 | Buffalo | 6 - 7 | Washington |
| 06/08/2012 | 01:00 | New Orleans | 17 - 10 | Arizona |